Opioid Induced Constipation Clinical Trials

Opioids are natural or synthetic chemicals that interact with opioid receptors on the nerve cells in the body and brain, and reduce feelings of pain. They are a class of drugs that include prescription pain relievers, synthetic opioids and heroin.


Pain medications including Percocet, Duragesic, Vicodin, Oxycontin, as well as many others are often used to treat pain conditions such as chronic lower back pain or osteoarthritis of the knee. As effective as these medications are, they often result in the unbearable side effect of constipation.


Clinical trials for people who suffer from opiate induced constipation offer new options to improve the lives of those living with opioid induced constipation. At CNS Healthcare, we occasionally offer opioid induced constipation clinical trials. Find out if an opiate induced constipation clinical trial is enrolling near you by selecting a location. Use the form on the page to schedule a free appointment to see if one of our trials is right for you.

Find A Currently Enrolling Opioid Induced Constipation Clinical Trial Near You:

More About Opioid Induced Constipation

Opioids increase the amount of time it takes stool to move through the gastric system. Opioid based pain medication has the ability to partially paralyze the stomach (gastroparesis) so that food remains in the digestive system for a longer period of time causing pain and discomfort.

Signs & Symptoms

  • Stools that are hard and dry (constipation)
  • Difficulty such as straining, forcing, and pain when defecating
  • A constant feeling that you need to use the toilet
  • Bloating, distention, or bulges in the abdomen
  • Abdominal tenderness, or pain