Diabetic Peripheral Neuropathy (DPN) Clinical Trials

Diabetic Peripheral Neuropathy is damage of the nerves in our bodies’ extremities (typically starting in the feet and legs) and can occur when there are chronic high levels of blood sugar in the body. These peripheral nerves are responsible for detecting pain, pressure, and differentiating between hot and cold. These particular nerves also have an effect on muscle strength and the way that the muscles move.


At CNS Healthcare we ‘re exploring improved treatments through diabetic peripheral neuropathy clinical trials which include nutritional supplements, non-addictive pain medicine, creams, ointments and more. Find out if DPN research is right for you by selecting a location from the list below and scheduling a no-cost appointment using the form on the page.  

Find A Currently Enrolling Diabetic (DPN) Peripheral Neuropathy Clinical Trial Near You:

More About Diabetic Peripheral Neuropathy

Common symptoms patients describe when they have Diabetic Peripheral Neuropathy include a loss of feeling or a general numbness of the feet, a burning sensation or a stabbing pain in an affected area, bone and joint deformities, significantly reduced or increased sensitivity to touch or temperature, and a loss of balance and coordination when standing or walking. Loss of sensation is the most common and sometimes only symptom of this condition, and is therefore imperative for those who are at risk to seek a diagnosis to reduce the risk of deformities or amputation. Although the damage caused by Diabetic Peripheral Neuropathy is a slow progression, it can steadily worsen over time especially when blood sugars are not well controlled.


Chronically elevated blood sugars is an important contributor to this condition, but there are other factors that should be considered as well, including age, duration of diabetes, smoking, alcohol use, and hypertension (high blood pressure). Other medical conditions and nutrition can contribute to the development of Diabetic Peripheral Neuropathy as well. It is important that high risk patients consult a specialist to determine if they have this condition so that they can begin treatment.


Signs & Symptoms

  • Numbness or reduced ability to feel pain or temperature changes
  • A tingling or burning sensation
  • Sharp pains or cramps
  • Increased sensitivity to touch — for some people, even the weight of a bed sheet can be agonizing
  • Muscle weakness
  • Loss of reflexes, especially in the ankle
  • Loss of balance and coordination
  • Serious foot problems, such as ulcers, infections, deformities, and bone and joint pain